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#Volatility

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A Late-Stage CETP Inhibitor Developed by NewAmsterdam Pharma Company N.V. timesofupdate.com/a-late-stage NewAmsterdam Pharma Company N.V., a biopharmaceutical entity based in the Netherlands, is conducting late-stage clinical evaluations of obicetrapib, a novel cholesteryl ester transfer protein (CETP) inhibitor. This article explores the pharmacol… #BCAResearch #CoverageFunds #FinancialWorld #Home #NewamsterdamPharmaCompanyNV #PresidentTrump #volatility #WallStreetAnalysts

#python #AI #portfolio #optimization #algorithm
#technology #tech
#stock #risk #volatility
#finance #fintech #stockmarket

Quant Risk-Return Analysis, Portfolio Optimization and Profitable Algo-Trading Strategies of Top 5 AI Stocks

A Deep Dive into Popular Risk-Return Gauges of Quant Finance, MPT/Black-Litterman Portfolio Optimization and Hybrid Algo-Trading Strategies (with Backtesting) of Top 5 AI Stocks: PLTR, CRM, AMD, ANET, and NVDA

#exploremore 👇

medium.com/@alexzap922/quant-r

"In a downturn, you don’t find momentum. You make it!" - Futurist Jim Carroll

In a time of volatility, uncertainty, and a lack of clarity, the most natural reaction is often the worst one: we do nothing.

We pause. We overthink. We wait for something to settle before we make a move. 

We seek clarity and wait.

We end up waiting a long time - because the irony of this is that clarity doesn’t come from waiting—it comes from moving.

That's the real secret to getting through this volatile time.

Over the past eight posts, we’ve explored what it takes to lead into the future when everything feels unstable: replacing fear with action, and nostalgia with vision. Challenging inertia through innovation, and stress through strategic resilience.  Leading with agility over indecision, and thinking globally, not locally. Things like that.

But none of that matters if momentum is missing. Because without motion and moving forward, there is no forward.

That's why you need to imprint this idea in your mind. “You don’t find momentum. You make it.” The future doesn’t reward the ones who paused the longest. It rewards the ones who moved—even just a little—when no one else was.

And here's a secret you should know - progress isn’t always dramatic.

Sometimes it’s quiet, compounding, and invisible to everyone except those who kept showing up. Let me be blunt  - inaction is a decision. And it’s usually the wrong one. When volatility strikes, many leaders freeze - the exact wrong thing to do. But the organizations that keep moving build momentum that outlasts the downturn.

Why do you need momentum, even if you don't know where you are going?

→ It allows for achievements – small wins fuel bigger moves
→ It shifts your mindset – which is what you need
→ It enables refinement – progress improves as you move
→ It reveals direction – showing key trends

The key isn’t to make a massive leap. It’s to take the first step—and then another. And another. Soon you are walking into tomorrow - and then running.

You are already well into the race to the future, while the rest haven't even figured out where the starting line is.

---

Futurist Jim Carroll is already well into the Acceptance stage of the 7 Stages of Economic Grief because he knows that it is the only sure way to deal with the relentless uncertainty that already defines 2025.

#Momentum #Action #Volatility #Future #Progress #Strategy #Clarity #Leadership #Resilience #Adaptation

Original post: jimcarroll.com/2025/04/decodin

"The future rewards those who adapt under pressure, not those who break because of it" - Futurist Jim Carroll

Over the last five days, I’ve shared how we lead ourselves and our organizations through this moment of global volatility—one shaped by economic uncertainty, political instability, and cultural retreat from the future.

Beginning by reaffirming belief in progress, even when it feels stalled

Confronting fear with action

Challenging nostalgia with vision

Spotlighting innovation as the antidote to inertia

Emphasizing the importance of thinking across time horizons—managing today while preparing for tomorrow

But there's something deeper that sits underneath all of that: pressure..
That’s the real test—managing this moment. Keeping our heads on straight. Not letting the negativity consume us or define our future. If there’s one constant through every downturn, disruption, or crisis, it’s this: stress is the defining force of the moment. And how we respond to that stress—organizationally, personally, and strategically—determines whether we fall back, freeze up, or forge forward into what’s next.

That’s why today, it’s not just about planning for the future.

It’s about learning to adapt under pressure.

Every moment of disruption applies pressure. And pressure reveals everything. It reveals which organizations and individuals have foundations that flex, and which ones crumble. It reveals leaders who focus forward—and those who fold under volatility.

Right now, we’re not just navigating an economic downturn. We’re navigating a world defined by compounding stress—market stress, leadership stress, and system stress. But stress, when met with strategy, becomes fuel for the future.

I’ve written about this before: “It’s in our response to volatility that our future is defined.”

The most future-ready companies don’t panic. They channel pressure into progress. They don’t crumble under stress—they restructure, refocus, and realign. They transform pressure into precision—cutting noise, not capacity. They rethink agility, not just in structure but in mindset. They use stress as a forcing function—to do what needed doing all along.

My advice is clear: You don’t rebuild your organization for the next crisis. You rebuild during this one—for the world that follows.

Stress is unavoidable. But breaking is not.

**#Adaptation** **#Pressure** **#Resilience** **#Stress** **#Future** **#Crisis** **#Leadership** **#Growth** **#Strategy** **#Volatility**

Original post: jimcarroll.com/2025/04/decodin

#30DayChartChallenge Día 11: Stripes! Mi versión: ¡El código de barras del pánico del mercado! 😱

Este gráfico muestra una línea de tiempo (1993-2025) donde cada raya vertical representa un día en que el VIX cerró ≥ 30 (¡alta tensión!).

El concepto clave aquí es el **Volatility Clustering**: la alta volatilidad no se distribuye uniformemente, ¡viene en rachas! Los densos grupos de rayas identifican visualmente las grandes crisis (Dot-com, GFC '08, Covid '20...). Los largos periodos en blanco son la calma relativa.

Es una forma directa de ver la *persistencia* y los *regímenes* de la volatilidad del mercado. ¡Olvida las medias simples, el estrés viene en oleadas! 🌊

🛠️ Hecho con #rstats, #ggplot2, #quantmod.
📂 Código/Repo: t.ly/-vd9u

The Financial Times just headlined "Whiplash" - exactly what I called Wednesday's market analysis.

Now China announces 125% tariffs on US goods.

This is precisely the cycle I described: policy shifts → positioning scrambles → price swings → repeat.

When you understand the mechanics, the headlines aren't surprising.

Read the full analysis for FREE that called it before the headlines: chaosandorderinsight.substack.com
#Markets #TradeWar #Volatility

China announces 125% tariffs on US goods, escalating the trade war dramatically.

This validates my Market Whiplash analysis—policy volatility rarely ends with the first move.

Bond markets were right to remain skeptical of yesterday's equity rally.

Mechanical market reactions continue in real-time as policy announcements accelerate.

chaosandorderinsight.substack.com
#Markets #TradeWar #Volatility

Hello Mastodon! I'm Marjorie, a former commodities trading MD now writing about market mechanics, volatility, and geopolitical trade dynamics.

After years of writing market analysis for institutional clients, I'm now sharing insights through my Chaos & Order newsletter.

If you're interested in what's happening beneath market headlines, I'd love to connect.

I'll also post from @MarjorieNadal

#30DayChartChallenge Día 10: ¡Buceando en la Distribución del VIX! 🌊

En lugar de solo ver la línea del VIX, hoy analizamos su "distribución de probabilidad" por Presidencia de EE.UU. (Clinton -> Trump 2º). ¡La forma lo es todo!

Usando #rstats y #ggplot2, estas densidades facetadas nos permiten investigar:
* Modos Dominantes: ¿Cuál era el nivel "normal" de VIX (el pico más alto)? ¿Cambió mucho?
* Multi-modalidad: ¿Hay evidencia de múltiples estados de volatilidad (picos secundarios) dentro de un mismo mandato? 🤔
* Riesgo de Cola: ¿Qué tan probable era el "pánico" (VIX > 35)? ¡Compara las colas derechas!

Estos patrones reflejan los distintos regímenes de volatilidad y la percepción del riesgo sistémico. No es solo el nivel, ¡sino la "estructura" de la incertidumbre lo que importa!

Datos: Yahoo Finance via #quantmod.
📂Código: t.ly/kikdo

"Inertia feels safe. Until it isn’t. Innovation feels risky. Until it wins." - Futurist Jim Carroll

Uncertainty rewards the inventive, not the indifferent.

Recessions test everything—strategy, structure, and above all, mindset.

You are going through all that right now with the wild whiplash of this moment in time. You can't easily define strategies straight in a world in which one moment the world is up and the next is down. You can't figure out a path forward when the path keeps changing. You can't plant a flag on a foundation of certainty where there is none.

But what you can do is commit to investing in your future through innovation.

Think about it - when the world turns volatile, most companies do the typical thing - they freeze. They cut everything. Delay everything. Protect what was. Go into a mode of delay. But others take a different route: they innovate—not recklessly, but intentionally. They adapt their offerings, reframe their markets, and lean into change.

History tells us who wins.

In past downturns, the most resilient companies continued to invest in R&D, product development, and digital transformation, even as they restructured costs elsewhere. They embraced frugal innovation—creating smarter, leaner, more relevant solutions with limited resources. They used the moment to reimagine offerings for evolving customer needs.

They didn’t innovate in spite of the crisis. They innovated because of it.

These companies weren’t reckless. They were strategic.

They used volatility as a forcing function to rethink how they deliver value—and to whom.

And the results speak for themselves - they:

- captured market share: Outpaced competitors by staying relevant during volatility.

- deepened customer loyalty: Met changing needs with smarter, faster solutions.

- reimagined offerings: Pivoted products and services to fit the moment.

- streamlined structures: Transformed operations to move with greater speed.

- accelerated disruption: Fast-tracked innovation that would’ve taken years otherwise.

Meanwhile, those that chose inertia? Most never caught up. Because innovation isn’t a luxury for good times. It’s a necessity for what comes next.

In the end, volatility favors those willing to reinvent—while inertia quietly takes the rest out of the game.

Which side of the curve will you be on?

---

Futurist Jim Carroll spoke on resilience and innovation in uncertainty at dozens of leadership meetings post ’01, again in ’08, and guided organizations again in ’20. He’s developed a comprehensive overview of how to move forward, not back, during an era of uncertainty. It’s being shared here and documented at tomorrow.jimcarroll.com

**#Innovation** **#Uncertainty** **#Resilience** **#Adaptation** **#Strategy** **#Crisis** **#Volatility** **#Future** **#Growth** **#Reinvention**

Original post: jimcarroll.com/2025/04/decodin