Mars розробляє стійкі сорти какао за допомогою CRISPR
# #CRISPR
https://gizchina.net/2025/08/12/mars-rozroblyae-stiyki-sorty-kakao-za-dopomohoyu-crispr/
https://www.europesays.com/us/129625/ Diabetic Man With Gene-Edited Cells Produces His Own Insulin—No Transplant Drugs Required #CRISPR #diabetes #Health #transplants #UnitedStates #UnitedStates #US
Le Cong, one of the pioneers of applying #CRISPR in eukaryotic cells, and his team now have developed an agent to apply #ChatGPT #LLM technology to automate and enhance CRISPR-based gene-editing design and data analysis.
In #nature Biomedical Engineering.
https://www.nature.com/articles/s41551-025-01463-z
Interesting paper on developing and using an #LLM based agent for #CRISPR based #GeneEditing design and experiments.
Microbial Fermentation Tech Market 2025
Expected to grow from $37.46B (2024) to $57.14B (2029) at an 8.7% CAGR.
Fueled by demand in biosimilars, fermented foods, alcoholic beverages, and synthetic biology.
Free sample:
https://www.thebusinessresearchcompany.com/sample.aspx?id=15862&type=smp
#Biotech #Fermentation #CRISPR #SyntheticBiology #FoodTech #BioPharma
Các nhà khoa học Nhật Bản sử dụng công nghệ CRISPR để loại bỏ hội chứng Down bằng cách nhắm mục tiêu vào nhiễm sắc thể thừa. Nghiên cứu mở ra hy vọng mới trong điều trị bệnh di truyền.
#khoahoc #di truyền #CRISPR #DownSyndrome #nghiencuu #science #genetics #hội chứng Down
"Researchers at the University of California San Diego, Johns Hopkins University, UC Berkeley and the University of São Paulo have developed a new method that genetically blocks mosquitoes from transmitting malaria. The study was published July 23, 2025 in the journal Nature."
https://today.ucsd.edu/story/stealth-genetic-switch-in-mosquitoes-halts-malaria-spread #InfectiousDisease #CRISPR
AI and CRISPR Revolutionize Cancer Treatment - David Linden on Theo Von
**Megatrend #12** - Personalized, Precision Medicine: "Tomorrow's cure lies not in a universal pill, but within our own genetic code." - Futurist Jim Carroll
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(Futurist Jim Carroll is writing a series on 30 Megatrends, which he first outlined in his book Dancing in the Rain: How Bold Leaders Grow Stronger in Stormy Times. The trends were shared in the book as a way of demonstrating that, despite any period of economic volatility, there is always long-term opportunity to be found. The book is now in print - learn more at dancing.jimcarroll.com)
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The one-size-fits-all era in medicine is ending. Treatments, nutrition, and wellness approaches tailored to individual genetic profiles are becoming the standard, not the exception. As with every post in this series, there's a PDF here that goes into more depth on this trend.
There's a little bit of duplication with some of the material covered in previous megatrends with this one, but it's important ot note that this trend is powerful enough on its own to deserve its own post.
What's it all about? We are combining what we might call 'next-generation genomic sequencing', AI, and CRISPR gene editing, to come up with a new health paradigm that involves 'fixing people before they are sick rather than after.' Why these 3 trends? The cost for genomic sequencing is collapsing, AI is accelerating the ability to do so, and gene editing allows us to correct the genetic causes of disease at the source.
Before going further, it's important to define the revolution by understanding two key terms.
The first is Personalized Medicine, which uses an individual's unique genomic, environmental, and lifestyle information to guide decisions for prevention, diagnosis, and treatment of disease. It's based on the idea that because no two individuals are the same, they should not receive the same healthcare.
The second term is Precision Medicine. While often used interchangeably, it more accurately describes the strategy of stratifying individuals into small populations based on shared characteristics. It focuses on identifying which healthcare and pharmaceutical approaches will be most effective for those small, specific groups of people, rather than creating unique treatments for each individual.
While its potential is immense, the transition to personalized medicine is not merely a technological upgrade but a disruptive force that challenges the foundational structures of healthcare delivery, research, and regulation.
Even so, over the long term, it's one of the biggest megatrend opportunities of our time.
**#Personalized** **#Medicine** **#Genomics** **#CRISPR** **#AI** **#Precision** **#Healthcare** **#Genetics** **#Innovation** **#Future**
Gentechnik-Debatte: Landwirte kämpfen mit Klimaschäden auf Feldern
Angesichts der Klimakrise wächst bei einigen Landwirten die Hoffnung auf gentechnisch veränderte Pflanzen – doch Kritiker warnen vor
Risiken.
Just mind bogglingly amazing - modern #GeneEditing therapies! Doesn't get more #PrecisionMedicine than this!
"First Personalized CRISPR Gene Editing Therapy Patient Baby KJ Discharged
Three hundred and seven days after he was first admitted to Children’s Hospital of Philadelphia (CHOP), the 10-month-old went home after being treated with a bespoke base editing approach"
#Science #CRISPR #genetics
https://www.insideprecisionmedicine.com/topics/precision-medicine/first-personalized-crispr-gene-editing-therapy-patient-baby-kj-discharged/
A Gene Editing Strategy to Repair Huntington's Defects
"A lot more studies would be needed before we can know if disrupting these repeats with a base editor could be a viable therapeutic strategy to treat patients. But being able to illuminate the biological consequences of interrupted repeats is a really useful and important milestone," explained senior study author Dr David Liu.
#CRISPR #genetics #research #biology #biotechnology #science #Huntingtons
I'd like to read more about DNA & CRISPR. The origins, the background story, but also how CRISPR works etc.
Does anybody know which book I should read? There are multiple books on the topic & it's hard for a layman to choose from.
My background is in IT & (Interaction) Design.
This is an example of what is being eliminated as Republicans in Washington, DC and this administration make catastrophic cuts to scientific research (among other things) to provide tax cuts to and curry favor with billionaires:
"World’s first patient treated with personalized CRISPR gene editing therapy at Children’s Hospital of Philadelphia"
https://www.pennmedicine.org/News/worlds-first-patient-treated-with-personalized-crispr-therapy
#ScienceMatters #science #CRISPR #antiscience #DOGE
What are the best ways these days for folks without institutional accounts to read recent journal articles that aren't open access? It's so disappointing not to be able to read papers like this that are all over the media.
For this one I even tried to make the free NEJM account but it didn't work.
Please don't say to email the authors.
Baby Is Healed With World’s First Personalized Gene-Editing Treatment.
The technique used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases.
https://www.nytimes.com/2025/05/15/health/gene-editing-personalized-rare-disorders.html?unlocked_article_code=1.Hk8.wt5y.1chNUwxx815P&smid=url-share&fbclid=IwY2xjawKUeChleHRuA2FlbQIxMABicmlkETBpcWpnVEtiZnJ0S3hTclJwAR4DmWeeHkLifw6xpi6qz_UxwoMN8cWOUSF5yPLITApHCR_Z8B-bCuZw8Q8A7A_aem_BZHhad4Od2mkYpN_1s0icQ #genetics #CRISPR #genetherapy
(Just another example of why we should treasure our researchers and scientists)
Good news from @npr, as shared by our @ScienceDesk. A baby born in Philadelphia last August with a life-threatening genetic disorder was successfully treated with a gene-editing infusion developed using CRISPR technology. His genetic defect appears to have been fixed, at least partially reversing his condition.
holy moly! a baby born with a rare and dangerous genetic disease is growing and thriving after getting an experimental gene editing treatment made just for them:
https://www.cbc.ca/news/health/gene-therapy-baby-pennsylvania-1.7536105
When KJ Muldoon was born at Children's Hospital of Philadelphia (CHOP) in August, doctors noticed that he was lethargic. They carried out tests that revealed he had a genetic metabolic disorder that leads to the buildup of ammonia and can cause brain damage and death. Gene sequencing helped them determine the exact location of the error that led to him being unable to make a vital enzyme. This allowed doctors to use CRISPR technology to create a treatment tailored specifically towards his unique mutation. After three infusions containing billions of gene editors, his defect appears to have been corrected and his condition, at least partially reversed. "This is an important first step towards an entirely new type of personalized medicine. I think it's going to utterly transform the way we practice medicine, particularly in the area of rare diseases," says Dr. Kiran Musunuru, a professor for translational research at the University of Pennsylvania, who worked on KJ's case. See the @npr story at the first link. There's a link to the original article in the New England Journal of Medicine at the second link.
