Hey folks

A friend of ours has been experiencing something odd that we've not seen before:

• Her estradiol (E2) pmol/L per mg level has been gradually rising over the last 305 days.

... and we lack the understanding of statistical analysis to be able to analyse it properly

All injections were done weekly, using estradiol enanthate compounded at 40 mg/mL from the same homebrewer.

We don't think markdown tables work in Glitch-SOC, so here's all the data we have in a non-tabular form.

Date: 2023-12-28
Volume: 0.13 mL
Dose: 5.2 mg
Trough: 724 pmpl/L
Pmol/L per mg: ~139

Date: 2024-03-26
Volume: 0.17 mL
Dose: 6.8 mg
Trough: 1272 pmpl/L
Pmol/L per mg: ~187

Date: 2024-10-28
Volume: 0.16 mL
Dose: 6.4 mg
Trough: 2491 pmpl/L
Pmol/L per mg: ~272

We're not sure how to use the data to model how to get her pmol/L per mg stable, rather than steadily increasing.

The desired aim is to keep her pmol/L trough roughly between 750 to 900 pmol/L, without it increasing steadily over time.

We think this might mean moving to a 8-10 day injection cycle and a lower dose (0.10 to 0.12 mL; 4 to 4.8 mg), but we are not sure how to do it.

Can anyone help us out here?

#DIYHRT #OpenHRT #injections #TransFem #StatisticalAnalysis #statistics #AskFedi #trans #transgender #estradiol #queer #LGBTQ+ #LGBTQIA+ #simulation #maths